How long does it take for avana50 to work, which contains the active ingredient avanafil, typically starts working within 15 to 30 minutes after taking the pill. This is similar to other erectile dysfunction (ED) medications like sildenafil (Viagra), but avanafil has the advantage of working faster and having a shorter onset time. If you're considering using Avana50 or any erectile dysfunction medication, it's important to follow the instructions provided by your healthcare provider for the best results. Always consult a doctor if you have any concerns or underlying health conditions.